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A macrophage-dominant PI3K isoform controls hypoxia-induced HIF1alpha and HIF2alpha stability and tumor growth, angiogenesis, and metastasis

Purich 53

In line with this, sustained exposure to high GH levels induces both hepatic and peripheral (muscular) resistance to the actions of insulin on glucose metabolism together with increased (or inadequately suppressed) lipid oxidation

Functionally, these findings correlated with reduced iron availability upon dexamethasone pretreatment after 24 h of erastin treatment as assessed by flow cytometry for FerroOrange staining (Fig